J. Michael Menke, PhD
michael.menke@gmail.com
4444 South Veneto
Mesa, AZ 85212
https://www.linkedin.com/in/jmichaelmenke/
phone: 520 301 0176
Experienced in clinical statistical analysis and program evaluation. Programming languages experience: R, SPSS, and SAS. Author of proposals and articles in program evaluation, health economics, and policy and outcomes research using most current tools in data analysis for better decision-making in product, provider, health system, medical and policy decisions, treatment development, and implementation. Have successfully led cross-functional research from conception through data analysis, interpretation, scientific writing, and publishing. TreeAge software for Markov Chain Monte Carlo analysis and economic modeling. Former clinician in diagnoses and procedure coding. Hands-on expertise in medical testing and screening, validation, and clinical trials. Innovative and experienced Bayesian analyst and meta-analyst. Longitudinal and survival data analysis; Cox regression survival analysis.
Professional Positions
Veterans’ Health Administration: A Finger Lakes Healthcare System June 2022 – present
Center of Excellence for Suicide Prevention
400 Fort Hill Avenue
Canandaigua, NY 14424
· Content expert, mortality from hypertension, Veteran’s Health Administration.
· Data analyst.
· R and SAS analysis of factors contributing to hypertension mortality of Vietnam veterans.
· Literature search.
· Hypothesis formation.
· Hypothesis testing by Cox regression survival analysis.
Menke Decision Sciences, LLC – Mesa, Arizona February 2022 – present
Senior methodologist, statistician, program evaluation, health economics and outcomes research
· Data analyst for device, early detection of Parkinson’s Disease.
· Data analyst for device, early detection of multiple sclerosis exacerbations.
Exact Sciences – Redwood City, CA and Madison, WI
Principal biostatistician, health economics and outcomes research. August 2021 to Feb 2022
· Complex statistical modeling for testing economic and clinical outcome models of colorectal cancer screening.
· Applied statistical consultant for medical affairs.
· Deriving gamma transition distribution parameters using maximum likelihood estimation algorithms in R programming language for modeling colorectal cancer screening.
Menke Decision Sciences, LLC – Mesa, Arizona October 2019 – August 2021
Senior methodologist, statistician, program evaluation, health economics and outcomes research
· Performed data analysis, and risk factors for acute cardiac events in firefighters. Patient reported outcomes, real world evidence, health economics and outcomes research. Primarily used R and SPSS for complex studies
· Designed, wrote, and led the team on asynchronous on-line course.
· Maintained item response theory critique of the patient-reported outcome on spine pain and dysfunction.
· Method for finding the most informative oral cancer salivary biomarkers cited in 2020 issue of Nature.
· Health outcomes design and validation of population-based health care interventions.
Clients:
· Saccadous, Scottsdale, AZ. October 2019 to present. In collaboration with Barrow Neurological Institute, Phoenix. Designed statistical analysis plan for testing medical device validation of early detection of Parkinson’s Disease. Current pilot phase will be scaled to national multicentered trial. Involved in all aspects of design study, statistical analysis plan, data quality review, medical test accuracy and positive predictive values from collected data. Data quality control and analysis. Measured sensitivity, specificity, AUC, positive predictive value, negative predictive value.
· Rowpar Pharmaceuticals, Scottsdale, AZ. December 2019 to present. Investigated effects of mouthwash on dental implant in post-surgical recovery and health dental health by measuring of plaque, gingivitis, and periodontitis. Lead analyst in data reformatting and merging complex dental data by extensive Excel macro coding into long and wide formats for analysis by generalized estimating equations and general and generalized linear models. Data quality control and analysis, tables, figures, scientific writing for publication. Biostatistician, statistical analysis plan, data analyst.
· Northridge Neuropathology Department, January 2021 to present. Northridge Hospital, California. Designed statistical study to identify biomarker changes immediately preceding severe multiple sclerosis exacerbation. Established statistical analysis plan, functioned as biostatistician and data analyst specializing in medical test accuracy and positive predictive values. Provided data quality control and analysis, Measured sensitivity, specificity, AUC, positive predictive value, negative predictive value.
· SoTech Ventures, Dallas, TX. January 2021 to June 2021. Medical device for rapid detection of COVID-19 using breathalyzer. Devised statistical analysis plan, analyzed data, calibrated screening accuracy and positive predictive values.
A. T. Still Research Institute – Mesa, AZ May 2016 – Oct 2019
Associate Director of Research
Principal investigator on PCORI grant investigating traumatic brain injury caregivers and survivors using natural language processing, patient reported outcome development, and psychometric analyses. Trained, led and mentored junior researchers in clinical outcomes, health economics, and epidemiology studies. Former chair of psychology department and associate director of research.
· Designed and implemented traumatic brain injury research based on natural language processing and sentiment analysis.
· Innovated method to screen for oral cancer with fewer salivary biomarkers.
· Economic analysis of optimal surgery strategies of a brain aneurysm, University of Washington.
· Liaised with scientists and vendors in cancer and traumatic brain injury biomarker research and began early-stage collaboration discussions at an international cancer conference in Singapore
· Made research alliances with brain injury foundations in Arizona, Washington state, and Oregon regarding collaborative research, research education, research execution in diagnosis, screening, detection of minor traumatic brain injury illness.
· Authored Chapter in Encyclopedia of Personality Differences: Evolution of altruism, Sociobiology.
Return to US and interviewing for jobs November 2015 – May 2016
Los Angeles, CA
International Medical University – Kuala Lumpur, Malaysia November 2012 – Nov 2015
Professor, Faculty of Medicine and Health, Head of Psychology
· Developed method for identifying and using the most informative (or efficient biomarkers) for oral cancer screening via applying psychometric assessment methods to meta-analyses, published in Biomarkers in Cancer (2017).
· Collected data on patient-reported outcome measure, currently in preparation for publication.
· Published innovative method for performing a comparative effectiveness meta-analysis, Spine 2014.
· Designed and executed meta-analysis for oral cancer medical screening, published 2017.
· Spearheaded grant funding for novel cancer biomarker meta-analysis and cross-cultural reporting of pain.
Critical Path Institute – Tucson, Arizona September 2010 – September 2011
Postdoctoral Research Fellow
· Developed patient reported outcome measures for meeting FDA guidelines in drug development.
· Screened biomarker accuracy for neurological diseases including Alzheimer’s disease, Parkinson’s syndrome and disease.
Arizona Cancer Center – Tucson, Arizona September 2009 – December 2010
Health Technology Research Analyst
· Performed meta-analysis of colorectal cancer screening and created 60-scenario simultaneous simulations for cost-benefit and cost-utility studies of types and sensitivities and specificities of colorectal cancer screening using Markov Chain Monte Carlo methods on TreeAge software. Cost-effective methods were formulated by patient, payer, and value of a statistical life to society perspectives.
· Created statistical model of cancer progression from polyps or flat lesions to disseminated cancer.
· Assessed impact, cost, value of statistical life, life-years saved of competing screening strategies.
Arizona Tobacco Education and Prevention Program – Tucson, Arizona January 2004 – September 2009
Health Technology Assessment Specialist
· ACCESS database design and maintenance of outcomes analysis, and reporting on cessation programs
· Wrote R language and LaTeX programs for auto-report generation of smoking cessation training outcomes after training health care professionals
· Adapted Bayesian indirect methods to compare literature best method for smoking cessation to identify the most effective smoking cessation medium: “doctor’s orders.”
EDUCATION, PROFESSIONAL DEVELOPMENT, & CREDENTIALS
PhD major, Program Evaluation and Research Methodology
University of Arizona College of Mind, Brain, and Behavior
PhD minor, Pharmaceutical Economics, Policy, and Outcomes Research
University of Arizona College of Pharmacy
Master of Arts, Program Evaluation and Research Methodology
University of Arizona College of Mind, Brain, and Behavior
Master of Arts, Applied Behavioral Science
Wright State University
Bachelor of Science, summa cum laude
Wright State University
Technical Skills:
Microsoft Office Suite, DataDesk, Bilog, Multilog, Excel
Artificial intelligence software: Cognobit, AI Labz
Program evaluation
R, SAS, SPSS statistical software
Advanced Statistics, Biostatistics and Data Analytics.
Data quality collection, cleaning, and analysis.
Epidemiological data outcomes and analysis
Patient reported outcome measurement (PROM) validation
Analysis plans, proposals, and methods.
Probabilistic and deterministic data modeling and simulation
Working and leading cross-functional project teams
Associations and Memberships
International Society for Pharmacoeconomic Outcomes Research
Formerly, American Evaluation Association
Formerly, Association for Psychological Science
Former member, Stanford University Spinal Research Group
Research mentorship and training in Malaysia
Certifications in meta-analysis, health outcomes and economics, and statistical services
Data matters: Data Curation, North Carolina State, August 7 - 11, 2017.
Reviewer
Reviewer for Statistics in Medicine
Reviewer for Journal of Methods and Measurement
Selected Publications:
Menke JM. What Chiropractic Research Teaches Us About the Replication Crisis in Science. https://www.skeptic.com/reading_room/what-chiropractic-research-teaches-us-about-replication-crisis-in-science/
Retrieved November 23, 2022.
Menke JM. Cracking history: chiropractic’s secret origin. Skeptic 27(3): 50-57, September 15, 2022.
Menke JM. The functional rating instrument: Twenty years of invalid measurement. Spine 47(7): 574-581, April 1, 2022.
Raghavan C., Beck CJ, Menke JM, Loveland, JE. Coercive controlling behaviors in intimate partner violence in male same-sex relationships: a mixed-methods study. Journal of Gay & Lesbian Social Services, 31:3, 370-395, 2019, DOI: 10.1080/10538720.2019.1616643
Menke J. M. Sociobiology. Chapter in Encyclopedia of Personality and Individual Differences. V. Zeigler-Hill, T. K. Shackelford (eds.), Springer International Publishing AG, Springer Nature, 2018. Retrieval: https://issuu.com/michael.menke/docs/sociobiology_copy on January 10, 2019.
Menke J. M. and Roy D. Methodology for Finding and Interpreting Efficient Biomarker Signals. Clinical Laboratory International, Dec 2018 – Jan 2019; 6 -10.
Menke JM, Ahsan MS, Suan PK. More Accurate Oral Cancer Screening with Fewer Salivary Biomarkers. Biomarkers in Cancer, 2017 Oct 17; 9:1 – 15.
Figueredo AJ, Garcia RA, Menke JM, Jacobs WJ, Gladden PR, Bianchi J, Patch EA, Beck CJA, Kavanagh PS, Sotomayor-Peterson M,
Jiang Y, and Li NP. The K-SF-42: A New Short Form of the Arizona Life History Battery. Evolutionary Psychology, Special Issue: Psychometrics and Variation in Human Life History Indicators, January-March 2017: 1–12.
Motlagh F, Ibrahim F, Menke JM, Rashid R, Seghatoleslam T, Habil H. Neuroelectro-physiological approaches in heroin addiction research: A review of literatures. J Neuroscience Research. 2016 Jan 8. doi: 10.1002/jnr.23703.
Menke JM. Deconstructing the tower of back pain babel. Physical Therapy Reviews, August 2015 issue, 20(4): 262-263.
Menke JM. Letter to the editor addressing limitations of null hypothesis significance testing. Spine 40(14): E856-E858, July 15, 2015.
Roffers SD, Menke JM, Morris DH. A somatovisceral reflex of lowered blood pressure and pulse rate after spinal manipulative therapy in the thoracic region. Asian Journal of Multidisciplinary Studies, 3(6): 30 – 36, June 1 2015.
Menke JM. Manual therapy researchers are misled by natural history and placebo effects. Letters, Spine Volume 39(23): 1997, November 1, 2014.
Menke JM. Do manual therapies help low back pain? A comparative effectiveness meta-analysis. Spine Volume 39(7) pp E463-E472, April 1 2014. Altmetric score: 194.
Ganasegeran K, Menke JM, Vasudeva Murthy C.R., Manaf MRA, Alabsi AM, and Al-Dubai SAR. Level and determinants of knowledge of symptomatic knee osteoarthritis among railway workers in Malaysia. BioMed Research International, Vol 2014, Article ID 370273, 9 pages http://dx.doi.org/10.1155/2014/370273, 2014.
Beck CJA, Menke JM, Figueredo AJ. Validation of a measure of intimate partner abuse (Relationship Behavior Rating Scale-Revised) using item response theory analysis. Journal of Divorce and Remarriage, 54:58-77, 2013.
Menke JM. Thinking inside the box: simple methods to evaluate complex treatments. Journal of Methods and Measurement in the Social Sciences, 2(1), 45-62, 2011.
Warholak TL, Hines LE, Song MC, Gessay A, Menke JM, Sherrill D, Reel S, Murphy JE, Malone DC. Medical, nursing, and pharmacy students’ ability to recognize potential drug-drug interactions: a comparison of healthcare professional students. Journal of the American Academy of Nurse Practice. 2011 Apr 23(4):216-21.
Warholak, T, Menke JM, Hines LE, Murphy JE, Reel S, Malone DC. A drug-drug interaction knowledge assessment instrument for health professional students: a Rasch analysis of validity evidence. Research in Social and Administrative Pharmacy, 7 (2011): 16-26.
Feise RJ, Menke JM. Functional rating index: a literature review. Medical Science Monitor 2010 Feb (16) 2, RA25-36.
Grieves B, Menke JM, Pursel K. Cost minimization analysis of low back pain claims data for chiropractic versus medicine in a managed care organization. Journal of Manipulative and Physiological Therapeutics 2009 Nov-Dec (32) 9: 734-739. Featured in MDLinx, Dec 14, 2009.
Menke JM. Bar patronage after a smoking ban. Journal of Drug Issues, Spring 2009: 401-416.
Beck CJA, Menke JM, O’Hara K, Figueredo AJ. The Relationship Behavior Rating Scale: validation and expansion of a revised measure of intimate partner violence. Journal of Divorce and Remarriage, 2009, 50(5): 295-308.
Gilles ME, Strayer LJ Leischow R, Feng C, Menke JM, and Sechrest L. Awareness and implementation of tobacco dependence treatment guidelines in Arizona: Healthcare Systems Survey 2000. Health Research Policy and Systems, 2008, 6:13.
Menke JM, Plaugher G, Carrari CA, Coleman RR, Vannetiello L, Bachman TR. Likelihood-evidential support and Bayesian analysis on a prospective cohort of children and adolescents with mild scoliosis under chiropractic management. Journal of the Arizona-Nevada Academy of Sciences, 2007, 39(2): 99-111.
Rowe DE, Feise RJ, Crowther ER, Grod JP, Menke JM, Goldsmith CH, Stoline MR, Souza TA, Kambach B. Chiropractic manipulation in adolescent idiopathic scoliosis: a pilot study. Chiropractic & Osteopathy 2006. 14:15 (21 August 2006), http://www.chiroandosteo.com/content/14/1/15.
Feise RJ, Donaldson S, Crowther ER, Menke JM, Wright JG. Construction and validation of the scoliosis quality of life index in adolescent idiopathic scoliosis. Spine, June 1, 2005, Volume 30(11) 1310-1315.
Fuhr AW and Menke JM. Status of Activator Methods chiropractic technique, theory, and practice. Journal of Manipulative and Physiological Therapeutics, February 2005; 28(2):135-155.
Menke JM. Integrative Medicine Research: What Medical Physicians Look For in a Chiropractor. Journal of the American Chiropractic Association, November 2002, 39(11):16-17.
Menke JM. Principles in integrative chiropractic. Journal of Manipulative and Physiological Therapeutics, May 2003 26(4): 254-272.
Feise RJ, Menke JM: Functional rating index: a new and reliable instrument to measure the magnitude of clinical change in spinal conditions. Spine, 2001;26(1):78-87.
Menke JM. Vital Topic: integrative medicine. Part II. Johns Hopkins Integrative Medicine Select, July 2003, 6(1): 1-4.
Menke JM. Vital Topic: integrative medicine. Part I. Johns Hopkins Integrative Medicine Select, June 2003, 5(12): 1-4.
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